Plant bioengineering & biomanufacturing

Engineered by science.
Built by nature.

Edible drugs for animals and humans, made in spirulina.
A multi-trait genetic platform, a biomanufacturing chassis, and a lead product for the pollination crisis.

The pollination crisis

Modern agriculture depends on bees.
Hive losses are catastrophic.

62%
U.S. honeybee colonies lost · June 2024 – March 2025
Largest single-year die-off on record
$577B
Annual global economic value of pollinators to crops
~75% of leading food crops depend on animal pollination
$2.6B
Annual replacement & lost-value cost from die-off
Borne directly by commercial beekeepers

Modern beekeepers absorb the cost of colony collapse without effective tools to prevent it.

The available toolkit — feed supplements, miticides, and chemical antibiotics — is reactive, coarse, and increasingly ineffective.

Phenova was built to change that.

The Weave platform

Multi-trait biomanufacturing,
delivered in spirulina.

Phenova combines four genetic technologies into a single, programmable transformation platform — and pairs it with a spirulina chassis (Arthrospira platensis) that's edible, GRAS-certified, and built for low-cost scale-up.

Technologies
  • Precision recombinases
  • Gene stacking
  • Tissue-specific expression
  • CRISPR / Cas9
Payloads
  • DNA
  • dsRNA
  • Nanobody
  • Any combination thereof
Hosts
  • Algae
  • Bacteria
  • Yeast
  • Plants

Lead product · ApiShield

From bees to biologics.

A spirulina-based feed additive that suppresses Deformed Wing Virus and other RNA pathogens in honeybees through orally-delivered, multi-trait expressed therapeutics. No injection. No veterinary intervention.

Chassis

Spirulina — an edible, photosynthetic microorganism with human food GRAS status, rapid scale-up, and contamination-resistant cultivation. Decades of algae-biofuel techno-economics inform our production model.

Mechanism

Bees consume biomass; expressed therapeutic payloads target viral and mite pathogens at the colony level.

Format

Syrup and solid feed-cake formulations, designed for drop-in compatibility with standard apiary feeding practices.

Get in touch

Let's bring it to market together.

For investors, partners, or media — reach out directly to any of us, or to the general inbox.

Paul Frankel
paul@phenovabio.com
Dr. Kasturi Dasgupta
kasturi@phenovabio.com
Jeff Steen
jeff@phenovabio.com

Or write to info@phenovabio.com.